Tranexamic Acid Tablets

Therapeutic Indication

Menorrhagia (heavy menstrual bleeding)

Postoperative hemorrhage

Dental surgery bleeding

Epistaxis (nosebleeds)

Trauma-related bleeding

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Tranexamic Acid

Tablet

Tranexamic Acid is an antifibrinolytic agent used to control excessive bleeding. It works by inhibiting plasminogen activation, thereby preventing fibrin degradation and stabilizing blood clots. It is widely used in gynecology, surgery, trauma, and dental procedures.

Speciality	Gynecology \| Hematology \| Surgery
Tags	Antifibrinolytic \| Hemostatic \| Gynecology
Strength	250 mg 500 mg
Packing Size	10 Tablets

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Mechanism

Tranexamic Acid competitively inhibits plasminogen activation, preventing fibrin degradation and stabilizing blood clots. This reduces bleeding in surgical, gynecological, and trauma-related conditions.

Pharmacokinetics

Bioavailability: ~34%
Peak plasma concentration: 3 hours
Half-life: ~3.1 hours
Excretion: Primarily via urine

Side Effects

Nausea, vomiting, diarrhea
Dizziness, headache
Rare: thrombotic events
Visual disturbances (rare)

Contraindication

Active thromboembolic disease
History of seizures
Hypersensitivity to Tranexamic Acid
Severe renal impairment

Interaction

Estrogens: ↑ risk of thrombosis
Anticoagulants: may reduce efficacy
Combined with fibrinolytics: antagonistic effect

Warning and Precautions

Monitor renal function during therapy
Use with caution in patients with thromboembolic risk
Discontinue if visual disturbances occur
Not recommended in patients with active clotting disorders